Rosie O’Donnell is celebrating a significant transformation in both her personal and professional life, particularly her recent weight loss journey as she embraces her new life in Ireland. Now at 63, the comedian has garnered attention by sharing candid updates on her experiences with her family, her lifestyle changes, and particularly, her dramatic body transformation.
O’Donnell revealed her weight loss on social media, showcasing the results of using Mounjaro, a medication primarily prescribed for Type 2 diabetes that has gained recognition for its side effect of aiding weight loss. In her post, she expressed her surprise at her physical changes, writing, “I can’t believe this is me now,” and using hashtags like ‘Mounjaro’ and ‘Body Dismorphia’ to convey her disbelief.
The weight loss journey is part of a broader lifestyle shift since relocating to Ireland at the beginning of 2025. O’Donnell has mentioned the changes in her daily life, including her new cooking routines, as she is now responsible for meal preparation for herself and her youngest child, Clay, 12. In a TikTok video shared in March 2025, she highlighted how shopping for clothes in Dublin has been a surprising experience, noting her shift from wearing an XL or 2XL to a size large. She humorously reflected on the novelty of wearing pants without an elastic waistband for the first time in years.
Her transformation has resonated with fans and fellow celebrities, with Kathy Griffin praising O’Donnell’s return to stand-up comedy and fans commenting positively on her experiences in Ireland.
Rosie O’Donnell’s journey illustrates a refreshing narrative of self-acceptance and personal growth, inspiring many others who may find themselves on similar paths. With her humor and resilience, O’Donnell continues to connect with her audience, reflecting a hopeful outlook on embracing change and celebrating progress in life.