Week 7 of the 2025 NFL season kicks off with an exciting match-up as the Indianapolis Colts travel to face the Los Angeles Chargers at 4:05 p.m. ET on CBS. Remarkably, the Colts currently hold the best record in the AFC after their recent victory over the Arizona Cardinals, where they triumphed 31-27.
Wide receiver Alex Pierce is making headlines as he returns from a two-game spell on the sidelines due to a concussion. In his first game back, he recorded two catches for 48 yards, showcasing his big-play potential as he maintains an impressive average of 19.9 yards per reception. With a 19.24 average depth of target (ADOT) ranking fourth among receivers with at least 50 routes run this season, Pierce’s ability to stretch the field is crucial.
However, the Colts could face challenges in the passing game this week, as his teammate Josh Downs has been ruled out with a concussion. This situation might lead to additional targets for Pierce, but it’s uncertain whether quarterback Daniel Jones will utilize him more effectively in the intermediate game.
When it comes to fantasy football considerations for Week 7, the advice for PPR leagues is to sit Pierce. His role as a deep-ball threat can make him a risky start, and so far this season, he hasn’t provided a performance strong enough to warrant a starting spot. Instead, pass-catchers like Michael Pittman and Tyler Warren have been more reliable options, likely continuing to draw the bulk of attention in the passing game.
In standard leagues, the same approach applies. Given Pierce’s boom-or-bust profile and the fact that he hasn’t yet delivered a must-start performance this season, it might be best to keep him on the bench for Week 7. As the season progresses, however, there is hope that Pierce will find his form and become a valuable asset for fantasy managers, particularly if his usage increases following Downs’ absence.