The college football 2025-26 season has been nothing short of unpredictable, showcasing several significant upsets that have left fans and bettors on edge. This trend underscores the volatile nature of betting on college football, where the unexpected can become reality at any moment. Let’s review some of the season’s most remarkable upsets as reflected in the betting markets.
One of the most surprising outcomes occurred on September 6, when South Florida overcame a significant 18-point underdog status to defeat Florida. Despite a solid performance from Florida’s quarterback DJ Lagway, the Gators faltered under penalties and missed scoring opportunities, allowing South Florida to clinch victory with a last-minute 19-yard field goal.
Another noteworthy upset involved Syracuse overpowering Clemson on September 20, despite being 17.5-point underdogs. Syracuse showcased their offensive prowess, amassing over 400 yards and maintaining their lead even after their quarterback, Steve Angeli, was sidelined by an injury in the third quarter. Clemson’s quarterback Cade Klubnick delivered an impressive 363 yards and three touchdowns, but his efforts were marred by an interception.
New Mexico’s victory over UCLA on September 12 highlighted the tumultuous season for the Bruins and their quarterback Nico Iamaleava. New Mexico’s dominance was evident as they secured 298 rushing yards and three touchdowns, leaving UCLA struggling in a game they never led.
The August 29 games witnessed Tarleton State’s dramatic win over Army and Central Michigan’s triumph over San Jose State. Both matches had tight finishes, with Tarleton State capitalizing on Army’s missed field goal in double overtime and Central Michigan overcoming San Jose State, who struggled with late-game field goal issues.
Stanford’s September 13 win against Boston College provided a standout moment for Frank Reich, who secured his first win as a collegiate head coach. A dominant second half, bolstered by Micah Ford’s standout performance, allowed Stanford to pull away from Boston College after a tight first half.
Lastly, Florida State stunned many by defeating Alabama on August 30. Despite Alabama entering as favorites, Florida State’s robust ground game and strategic plays led them to a convincing victory, marking a difficult start to the season for Alabama’s head coach Kalen DeBoer.
These surprising turnarounds illustrate the thrill and unpredictability inherent in college football, where underdogs frequently rewrite expectations and deliver unforgettable performances. As the season progresses, more surprises undoubtedly await, keeping fans and bettors alike on the edge of their seats.