The San Francisco 49ers made a significant impact during the 2025 NFL Draft with a defense-centric approach, selecting five defensive players to begin the event. This strategy emphasized bolstering their defensive capabilities with notable picks including three defensive linemen: Mykel Williams in the first round, Alfred Collins in the second, and C.J. West in the fourth round.
The trio played crucial roles throughout the season, with Williams becoming a primary starter until he unfortunately suffered a torn ACL. Collins overcame an initial slow start to integrate effectively into the team’s rotation, while West, despite dealing with injuries, contributed significantly due to the team’s depleted defensive line.
Looking ahead to the 2026 season, each of these players is expected to be instrumental as the 49ers aim to enhance their squad. The defensive line may still be a focus in the upcoming draft, especially if a standout defensive tackle becomes available. However, there are also indications that the team might shift its focus to fortifying the offensive line this time around.
While major overhauls along the offensive line are not necessary, the impending need for a long-term replacement for veteran left tackle Trent Williams is becoming evident. At 38, Williams is speculated to be nearing retirement, prompting considerations for a successor. Additionally, there may be a need to fill the guard position, especially with Spencer Burford entering free agency.
In his recent mock draft, ESPN’s Matt Miller projected that the 49ers would select Caleb Lomu, a standout offensive tackle from Utah, at the No. 27 pick. Miller highlighted Lomu’s impressive track record, noting he hasn’t allowed a sack since 2024 and possesses the agility required for success in the 49ers’ outside zone scheme. At 6 feet 6 inches and 308 pounds, Lomu also has the potential for further physical development.
Miller’s projections continued into the second round, suggesting the 49ers draft Logan Jones, a center from Iowa, at the No. 54 pick. Addressing the offensive line’s requirements is essential for the 49ers to maintain their status as Super Bowl contenders. Although Jake Brendel is established as the current center, Jones could fill a need for guard depth and provide youth to the offensive front.
Analyzing the 2025 offensive line, it’s evident that the 49ers have cultivated talent from various rounds of the draft. While three starters were products of their draft strategy, none were first or second-round picks, highlighting the team’s ability to identify and develop talent regardless of their draft position. With continued investment in both defensive and offensive lines, the 49ers look poised to remain competitive in their pursuit of a championship.