Patrick Dempsey has expressed his deep sorrow over the health struggles of his former Grey’s Anatomy co-star Eric Dane, who is currently battling amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease. Dempsey, known for his role as Derek Shepherd opposite Dane’s Mark Sloan, praised Dane for his strength and resilience in the face of such adversity.
In an interview with Parade, Dempsey revealed that he has been maintaining contact with Dane, sharing recent conversations and messages. “It’s very hard for him, but I do try to stay in touch and see how he’s doing,” Dempsey remarked. He emphasized Dane’s bravery in fighting the disease, stating, “He’s been incredibly courageous in the face of this horrible disease. He’s such a wonderful human being. He has such a great sense of humour, and he’s so intelligent. I’ve always enjoyed working and being around Eric.”
Dempsey described the situation as “heartbreaking,” not only for Dane but also for his family, highlighting the rapid progression of ALS and its physical toll. However, he commended Dane’s ability to bring positivity to his struggle, saying he is using his platform to shed light on the disease.
While Dempsey had hopes of involving Dane in his new thriller series, Memory of a Killer, he acknowledged that the progression of Dane’s illness made participation difficult. Nevertheless, he expressed happiness that Dane is still taking on roles, noting his guest appearance in the medical drama Brilliant Minds, where he plays a firefighter grappling with his own ALS diagnosis.
Dane, 53, was diagnosed with ALS in April 2025 after enduring months of medical evaluations. He has openly shared the impact of the disease, including the loss of function in his right arm and hand, and has been seen in public using a wheelchair.
This poignant update on Eric Dane serves as a reminder of the challenges faced by those dealing with ALS, while also highlighting the strength and support found in friendships during difficult times.